Probably ignition. could be plugs,plug leads,ignition coils, wiring, ECU. The coils (ONE PER 2 PLUGS) are known to fail on these MODELS as is the wiring loom. they are located below the inlet manifold. If left they can blow the ECU! Replace both even if only one is gone. thats my GUESS and its only a guess!!!
I've just solved the problem of misfiring with my C180 through elimination.
The following items were replaced: -
1) Complete Exhaust inc CAT Problem remained - needed done anyway
2) 2no Ignition Coils Problem remained
3) MASS Problem remained
4) Ignition Leads including plug caps under the coils and air filter RESULT Problem disappeared
I suggest the leads inc the caps total cost approx £38 from Euro Car Parts. If problem remains do the coils.