D
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I recall having so called "tubular" tyres on (Campagnolo) rims in the 60s. I believe the tyres were supposed to be disposable but as a teenager with limited money, I repaired punctures. The tyre was stitched closed on the inner circumference and once we’d repaired the puncture it had to be sewn up again (with dental floss) and glued back onto the rim.Ah OK, so you'd more likely end up with a slow puncture (as often happens with car tyres) rather than a flat.
Have to say I was shocked how thin and flexible these big tyres (Schwalbe Smart Sam 27.5x2.60) are. Tubeless ones must surely be thicker.