Found this on an American forum, this was after everyone had tried the reset method.
Had this exact issue with my 2015 E550 coupe.
Here is the description of the issue :
With Left Front window fully up, when the Left Rear window commanded fully up, it will go full up >> then it went down by 2 inches when the window switch released.
I have to keep repeating the "UP" command 3 times and the Left Rear window finally stays fully UP.
Also noted, the Left Rear window doesn't do the 2" roll down when the door is opened.
I tried the suggested window reset method, after stubborn four time attempts, all windows works normally . . . . until the next morning, the issue came back.
I ordered the P/N 2079004400 Desc : Rear Quarter Window Regulator (USED) from Pacific Motors. Price : $49.99 Delivered in 2 days.
Mercedes MRSP varies at around $350.
This part is located in the trunk, Left side behind the carpeting. Only need to remove one plastic button holding the carpeting and with a flashlight, it is easily accessible with one hand.
Remove the two connectors > remove the regulator > install the regulator > install the two connectors > do the window reset procedure > OK,
FYI, I decided to disect the defective regulator apart. No visible damage or corrosion or anything defective noticed. The two connectors were clean.
Another FYI, this regulator failed at 3(three) days after the car warranty EXPIRED. Go figure !
The dealer asked me if I want a diagnostic for $184 ++ and the part cost. Obviously, that didn't happen.
I hope this helps you guys.