Kerb weight on 109 Vito is 1818kg, kerb on a E280 1695kg, not much difference, also some Vito's have alloys? When I insured my Vito they classed it as an MPV as it has 6 seats.
Im unsure of alloy wheel spec difference but a loaded 280 at circa 2220kg with a top speed of 149mph, I struggle to see they would not be suitable. I guess an issue with an insurance company I should check.
Purely on the original question.... I guess these would physically fit?