If the seats you are replacing are also memory seats, from another same-version W212 (ie both pre-or post-facelift) they should be plug and play. If not, the memory is stored in the control units in the doors, I think, so you might need to change those, and you may need to have the front SAM coded, though I think it's more likely that you won't. I don't know about the loom.
Just fit them and see what functions you have, or have not, then take it from there.